University of Galway Theses (Research Masters Theses)
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Synthesis and characterisation of new metal-organic frameworks as carriers of antibacterial agents
(NUI Galway, 2024-04-18)Metal Organic Frameworks are highly porous, crystalline materials that have been used for a multitude of applications, with drug delivery and sensing at the forefront. These frameworks are extremely versatile and can ... -
Application of Ulva biomass for bioremediation of wastewater
(NUI Galway, 2024-04-18)The remarkable growth rate and environmental adaptability of Ulva species have attracted considerable interest for their potential applications in aquaculture and bioremediation. Ulva's capacity to absorb nutrients ... -
A 3-D radiative transfer analysis of AGB winds
(NUI Galway, 2024-04-16)The chemical enrichment of the interstellar medium is driven by stars of low to intermediate masses shedding their external layers through powerful stellar winds. Eventually, after many years in this phase, the core of ... -
In vitro model development for pulsed-field ablation treatment of atrial fibrillation
(NUI Galway, 2024-04-15)Atrial fibrillation is the most common type of cardiac arrhythmias in humans, mostly based on hyperexcitation of specific areas in the atrium that results in dyssynchronous atrial contraction, leading to severe ... -
Analysing bovine sperm cells using flow cytometry
(NUI Galway, 2024-04-10)The accurate assessment of bull fertility is extremely important to the beef and dairy industry. In recent years, flow cytometry has become the dominant approach in sperm evaluation and is increasingly being used for quality ... -
Boundary behaviour in the Irish Bronze Age: A study of social and ritual practices in the mid-late Bronze Age
(NUI Galway, 2024-04-08)The purpose of this thesis is to gain an insight into how boundaries were understood and utilised in the social and ritual lives of Bronze Age people. Boundaries are known in many forms, from visible physical linear ... -
Developing a three dimensional (3D) in vitro model of adrenocortical carcinoma (ACC)
(NUI Galway, 2024-04-05)Adrenocortical carcinoma (ACC) is a rare orphan disease and a rare cancer which carries a poor prognosis. The only licensed pharmacological treatment is mitotane, an insecticide. Typically, 2D cell culture models have ... -
Intraguild impact of the invasive Noble false widow spider Steatoda nobilis (Thorell, 1875) in Ireland
(NUI Galway, 2024-04-04)With rapid urbanisation during the Anthropocene, several generalist spider species have adapted to synanthropic microhabitats and have established large populations outside of their native ranges. On the island of ... -
Exploring advanced methodologies for the generation of synthetic data
(NUI Galway, 2024-03-21)In the field of computer vision and machine learning the need for high-quality diverse data sets are crucial. However, acquiring such data sets with detailed ground truth can be challenging. This problem led to the ... -
The impact of cognitive dysfunction on the occupational performance of cancer survivors post chemotherapy
(NUI Galway, 2024-03-13)Background: Cancer rates are increasing globally. Survivorship is also rising due to advancements in early detection and treatment. Chemotherapy is a common anti-cancer treatment with adverse effects reported due to its ... -
Large-scale production of engineered Extracellular Vesicles (EVs) in a serum-free continuous culture bioreactor
(NUI Galway, 2024-02-26)Extracellular vesicles (EVs) are nanoparticles produced by cells that facilitate intercellular communication through cargo transfer. When isolated from a biocompatible cell source, EVs can deliver therapeutic interventions ... -
Gradient-index lenses: Symplectic ray tracing and optical testing
(NUI Galway, 2024-02-22)The chief objective of this thesis is to provide an introduction to symplectic numerical methods and how they may be applied to optical problems, particularly for tracing rays within gradientindex (GRIN) optics. Specifically, ... -
Development and performance of a serological enzyme-linked immunosorbent assay (ELISA) for ruminant liver fluke disease
(NUI Galway, 2024-02-02)Fasciola hepatica, also known as the liver fluke, is the causative agent of fasciolosis. It is classified by the World Health Organisation as a neglected tropical disease, affecting both humans and livestock globally. ... -
Enhancing blood circulation time and performance of nano-drug delivery systems using nanoparticles and hydrogels
(NUI Galway, 2024-01-26)Mesoporous silica nanoparticles (MSNs) and hydrogels are some of the most sought-after methods of nano-drug delivery systems. Properties such as high biocompatibility, selectivity and loading capacity are among the many ... -
Mechanistic and kinetic study on the anomerisation reaction and application in pharmaceutical research
(NUI Galway, 2024-01-08)It is becoming increasingly apparent that carbohydrate-based pharmaceutically active compounds (PACs) play a key role in pharmaceutical advancement. Many new carbohydrate-based PACs have recently been developed with a ... -
An online tool for guiding bus fleet decarbonisation through green hydrogen and electrification
(NUI Galway, 2023-12-18)The transition to zero emission bus (ZEB) fleets is accelerating, and bus fleet operators are faced with no choice but to plan their decarbonisation approach now. Two prevalent ZEB options are battery electric buses (BEBs) ... -
Application of flow cytometry and membrane inlet mass spectrometry as tools to assess dimethyl sulfide produced in emiliania huxleyi (CHC108) cultures
(NUI Galway, 2023-12-04)Dimethyl sulphide (DMS) is a key component in the global sulphur cycle with emphasized significance in areas away from anthropogenic sources. Phytoplankton produce DMS when under stress as a defence mechanism from ... -
Reading between the 'likes': Intertextuality and meaning in neo-Assyrian expressions of similarity, metaphorical identity, and analogy
(NUI Galway, 2023-10-09)Figurative language is, in essence, the act of synthesising disparate concepts into one communicative image. Rather than merely a poetic technique, this process is fundamental in general understanding and expression ... -
Exploring the perceived factors affecting participation in rugby for children with disabilities using the ‘F-words in child development’ framework: A mixed methods study
(NUI Galway, 2023-10-09)Objective: The aim of this study was to explore the perceived facilitators and barriers to participation in rugby for children with disabilities from the perspective of three relevant stakeholders; parents of children ... -
Developing and implementing a l-openspim platform using in-air optics and measurement of tissue temperature changes
(NUI Galway, 2023-10-07)Relative to other microscopy techniques, light sheet fluorescence microscopy is widely accepted due to its ability to provide optical sectioning, higher speed, larger field of view, lesser photobleaching, and physiological ...